Once-weekly Nplate® is a platelet booster that works with your body to create more platelets. Nplate® is used after steroids and does not work by suppressing the immune system. Instead, it increases the activity of the cells that naturally produce platelets.
For some adults, taking Nplate® may lead to treatment-free remission, meaning platelet counts stay above 50,000 for at least 6 months after stopping ITP treatment
Watch the video to see Nplate® in action
Platelets are made by cells in the bone marrow. The amount of platelets your body makes is controlled by a protein called thrombopoietin, or TPO. In people with ITP, the amount of TPO is not high enough.
Nplate® works like TPO, telling the bone marrow to make more platelets, which can help reduce the risk of bleeding in people with ITP.
NO KNOWN DRUG INTERACTIONS OR LIVER MONITORING
EAT WHEN AND WHAT YOU WANT
Can be taken with or without food
ENJOY CALCIUM-RICH FOODS LIKE DAIRY
ONLY ONCE- WEEKLY INJECTION,
No need to remember daily pills
Nplate® has been proven to BOOST AND SUSTAIN PLATELETS
in 5 clinical studies of adults and children with ITP
Your doctor will help you understand how long you can expect to receive treatment for ITP. It's important to keep your platelets above 50,000 to reduce the risk of bleeding. If your platelets respond well to Nplate®, you may be able to go off treatment.
It's important to talk to your doctor
about treatment decisions.
Important Safety Information
What is the most important information I should know about Nplate®?
Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
Higher risk for blood clots:
What are the possible side effects of Nplate®?
How will I receive Nplate®?
Nplate® is given as an injection under the skin (subcutaneous) one time each week by your healthcare provider. Your healthcare provider will check your platelet count every week and change your dose of Nplate® as needed. This will continue until your healthcare provider decides that your dose of Nplate® can stay the same. After that, you will need to get blood tests every month. When you stop receiving Nplate®, you will need blood tests for at least 2 weeks to check if your platelet count drops too low.
APPROVED USES
Nplate® is a prescription medicine used to treat low blood platelet counts (thrombocytopenia) in:
Nplate® is not for use in people with a precancerous condition called myelodysplastic syndrome (MDS), or low platelet count caused by any condition other than immune thrombocytopenia (ITP). Nplate® is only used if your low platelet count and medical condition increase your risk of bleeding. Nplate® is used to try to keep your platelet count about 50,000 per microliter in order to lower the risk for bleeding. Nplate® is not used to make your platelet count normal. It is not known if Nplate® works or if it is safe in people under the age of 1.
Please see Prescribing Information and Medication Guide for more information about Nplate® on Nplate.com.
References
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Important Safety Information
What is the most important information I should know about Nplate®?
Worsening of a precancerous blood condition to a blood cancer (leukemia): Nplate® is not for use in people with a precancerous condition called myelodysplastic syndromes (MDS), or for any condition other than immune thrombocytopenia (ITP). If you have MDS and receive Nplate®, your MDS condition may worsen and become an acute leukemia. If MDS worsens to become acute leukemia you may die sooner from the acute leukemia.
Higher risk for blood clots:
